Variant effect prediction
Disease-causing variant effects are to be quantified on transmembrane protein structures. ex. molecule: 1TQN.cif.
Jul 1, 2024
PROTAC off-target effect prediction
PROTAC can generate off-target toxicity. This project aims to predict the off-target effects. ex. molecule: PRDCC_000001.cif
Jul 1, 2024
Small molecule-mediated targeting of microRNAs for drug discovery: Experiments, computational techniques, and disease implications
Jan 1, 2023
DeepdlncUD: Predicting regulation types of small molecule inhibitors on modulating lncRNA expression by deep learning
Jan 1, 2023
Improved sequence-based prediction of interaction sites in α-helical transmembrane proteins by deep learning
Jan 1, 2021
DeepHelicon: Accurate prediction of inter-helical residue contacts in transmembrane proteins by residual neural networks
Jan 1, 2020